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KMID : 0357920060400020151
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Korean Journal of Pathology
2006 Volume.40 No. 2 p.151 ~ p.155
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Follicular Lymphoma with Monoclonal Plasma Cell Differentiation - A Case Report -
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Kim Hyun-Chul
Kim Ae-Ree
Kim In-Sun
Lee Young-Seok
Kim Han-Kyeom
Yeom Bom-Woo
Choi Jung-Woo
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Abstract
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We present a case of recurrent follicular lymphoma with an extensive plasma cell component involving infra-auricular lymph nodes in a 64 year-old woman. Immunohistochemical staining showed a strongly positive reaction of the follicles with CD20, bcl-2, bcl-6, CD10 and CD21 on the first biopsy specimen. The intrafollicular and interfollicular plasma cells showed monoclonality for IgG heavy chain and lambda light chain. The histological and immunohistochemical findings in the recurrent tumor were identical with those of the original. Discussion is focused on the importance of the differential diagnosis between reactive lymphoid hyperplasia and other lymphomas having plasmacytic differentiation.
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KEYWORD
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Malignant lymphoma, Follicular lymphoma, Plasma cells
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